GSK 3008348 (hydrochloride), CAS [[1629249-40-6]]

Produktübersicht

• Artikelname: GSK 3008348 (hydrochloride), CAS [[1629249-40-6]]
• Artikelnummer: MCE-HY-19767A
• Hersteller Artikelnummer: HY-19767A
• Alternativnummer: MCE-HY-19767A-5MG,MCE-HY-19767A-25MG,MCE-HY-19767A-1MG,MCE-HY-19767A-100MG,MCE-HY-19767A-50MG,MCE-HY-19767A-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GSK 3008348 hydrochloride is a small molecule antagonist of integrin alphavbeta6 with IC50 values for alphavbeta6, alphavbeta1, alphavbeta3, alphavbeta5, and alphavbeta8 are 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. GSK 3008348 hydrochloride can target the alphavbeta6 integrin, inhibit TGF-beta activation, and thereby alleviate the fibrotic process. GSK 3008348 hydrochloride prevents the binding of the foot-and-mouth disease virus (FMDV) to the alphavbeta6 integrin receptor on the surface of host cells, thereby inhibiting the entry of the virus. GSK 3008348 hydrochloride can be used for research on pulmonary fibrosis and various types of cancer[1][2][3].

Produkteigenschaften

• Reinheit: 99.86
• CAS Nummer: [1629249-40-6]
• Formel: C29H37N5O2.xHCl
• Target-Kategorie: Integrin,TGF-beta Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound