Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC)[1][2].
Molekulargewicht:
738.29
Reinheit:
99.80
CAS Nummer:
[139504-50-0]
Formel:
C35H48ClN3O10S
Target-Kategorie:
ADC Payload,Microtubule/Tubulin
Anwendungsbeschreibung:
ADC Related
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