DS-8587 is a new fluoroquinolone with significant antibacterial activity. The MIC value of DS-8587 against clinically isolated amoxicillin-resistant Bacillus strains is superior to ciprofloxacin and levofloxacin. The antibacterial activity of DS-8587 is less affected by adeA/adeB/adeC or abeM efflux pumps, and has more advantages than ciprofloxacin. DS-8587 has a lower single-step mutation frequency than ciprofloxacin. DS-8587 may be an effective drug for inhibiting amoxicillin-resistant Bacillus infections[1].
Molekulargewicht:
493.90
CAS Nummer:
[1356918-39-2]
Formel:
C21H27ClF3N3O5
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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