Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect[1][2].
Molekulargewicht:
399.42
Reinheit:
99.53
CAS Nummer:
[1352608-82-2]
Formel:
C22H18FN7
Target-Kategorie:
TGF-beta Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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