Iptacopan (hydrochloride hydrate), CAS [[2447007-60-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Iptacopan (hydrochloride hydrate), CAS [[2447007-60-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-200854
• Hersteller Artikelnummer: HY-200854
• Alternativnummer: MCE-HY-200854-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: LNP023 (hydrochloride hydrate)

Produktbeschreibung

Iptacopan (LNP023) hydrochloride hydrate is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan hydrochloride hydrate exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan hydrochloride hydrate can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)[1][2][3].

Produkteigenschaften

• Molekulargewicht: 476.99
• CAS Nummer: [2447007-60-3]
• Formel: C25H33ClN2O5
• Target-Kategorie: Complement System

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1