BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Ralpha co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis[1][2][3].
Molekulargewicht:
259.09
Reinheit:
99.94
CAS Nummer:
[3104965-33-2]
Formel:
C10H8Cl2N2O2
Target-Kategorie:
Interleukin Related,STAT
Anwendungsbeschreibung:
MCE Product type: Reference compound
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