4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible[1].
Molekulargewicht:
98.11
Reinheit:
99.97
CAS Nummer:
[25222-43-9]
Formel:
C4H6N2O
Target-Kategorie:
Drug Metabolite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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