(S,R,S)-AHPC-Me (dihydrochloride), CAS [[2504950-56-3]]

Produktübersicht

• Artikelname: (S,R,S)-AHPC-Me (dihydrochloride), CAS [[2504950-56-3]]
• Artikelnummer: MCE-HY-42424A
• Hersteller Artikelnummer: HY-42424A
• Alternativnummer: MCE-HY-42424A-500MG,MCE-HY-42424A-5G,MCE-HY-42424A-100MG,MCE-HY-42424A-1G,MCE-HY-42424A-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: VHL ligand 2 (dihydrochloride), E3 ligase Ligand 1 (dihydrochloride)

Produktbeschreibung

(S,R,S)-AHPC-Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me dihydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 [2].

Produkteigenschaften

• Molekulargewicht: 517.51
• Reinheit: 99.84
• CAS Nummer: [2504950-56-3]
• Formel: C23H34Cl2N4O3S
• Target-Kategorie: Ligands for E3 Ligase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound