EN450, CAS [[793719-01-4]]

Produktübersicht

• Artikelname: EN450, CAS [[793719-01-4]]
• Artikelnummer: MCE-HY-49444
• Hersteller Artikelnummer: HY-49444
• Alternativnummer: MCE-HY-49444-5MG,MCE-HY-49444-10MG,MCE-HY-49444-10MMX1ML,MCE-HY-49444-100MG,MCE-HY-49444-500MG,MCE-HY-49444-50MG,MCE-HY-49444-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-kappaB. EN450 interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D. EN450 induces the ternary complex formation between UBE2D and NFKB1. EN450 exerts its anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism[1].

Produkteigenschaften

• Molekulargewicht: 288.76
• Reinheit: 98.59
• CAS Nummer: [793719-01-4]
• Formel: C11H13ClN2O3S
• Target-Kategorie: E1/E2/E3 Enzyme,Molecular Glues,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound