Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.Mavorixafor trihydrochloride can be used for the study of WHIM syndrome[1].
Molekulargewicht:
458.86
Reinheit:
99.75
CAS Nummer:
[2309699-17-8]
Formel:
C21H30Cl3N5
Target-Kategorie:
CXCR,HIV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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