A-769662 is a AMP-activated protein kinase (AMPK) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 µM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 µM). A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes[1][2][3][4].
Molekulargewicht:
360.39
Reinheit:
99.33
CAS Nummer:
[844499-71-4]
Formel:
C20H12N2O3S
Target-Kategorie:
AMPK
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
