Crizotinib (Standard), CAS [[877399-52-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: Crizotinib (Standard), CAS [[877399-52-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-50878R
• Hersteller Artikelnummer: HY-50878R
• Alternativnummer: MCE-HY-50878R-10MG,MCE-HY-50878R-5MG,MCE-HY-50878R-25MG,MCE-HY-50878R-50MG,MCE-HY-50878R-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-02341066 (Standard)

Produktbeschreibung

Crizotinib (Standard) is the analytical standard of Crizotinib. This product is intended for research and analytical applications. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].

Produkteigenschaften

• Molekulargewicht: 450.34
• CAS Nummer: [877399-52-5]
• Formel: C21H22Cl2FN5O
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Autophagy,c-Met/HGFR,Reference Standards,ROS Kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards