Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
393.44
Reinheit:
99.99
CAS Nummer:
[183321-74-6]
Formel:
C22H23N3O4
Target-Kategorie:
Autophagy,EGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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