7-Nitroindazole is a selective and BBB-penetrable inhibitor of nitric oxide synthase (NOS) (IC50 = 0.47 µM in mouse cerebellum). 7-Nitroindazole does not affect blood pressure or endothelium-dependent relaxation while inhibiting nNOS in experimental animals. 7-Nitroindazole has anti-injurious and neuroprotective properties, and can be studied in research for neurological diseases such as Parkinsons disease[1][2][3][4].
Molekulargewicht:
163.14
Reinheit:
99.09
CAS Nummer:
[2942-42-9]
Formel:
C7H5N3O2
Target-Kategorie:
NO Synthase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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