Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2].
Molekulargewicht:
585.61
Reinheit:
99.94
CAS Nummer:
[226700-79-4]
Formel:
C25H36N3O9PS
Target-Kategorie:
Drug Intermediate,HIV,HIV Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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