Lenalidomide (hemihydrate), CAS [[847871-99-2]]

Produktübersicht

• Artikelname: Lenalidomide (hemihydrate), CAS [[847871-99-2]]
• Artikelnummer: MCE-HY-A0003B
• Hersteller Artikelnummer: HY-A0003B
• Alternativnummer: MCE-HY-A0003B-10MMX1ML,MCE-HY-A0003B-1G,MCE-HY-A0003B-500MG,MCE-HY-A0003B-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CC-5013 hemihydrate

Produktbeschreibung

Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].

Produkteigenschaften

• Molekulargewicht: 268.27
• Reinheit: 99.98
• CAS Nummer: [847871-99-2]
• Formel: C13H14N3O3.5
• Target-Kategorie: Apoptosis,Ligands for E3 Ligase,Molecular Glues

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1