Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
Molekulargewicht:
259.26
Reinheit:
99.98
CAS Nummer:
[191732-72-6]
Formel:
C13H13N3O3
Target-Kategorie:
Apoptosis,Ligands for E3 Ligase,Molecular Glues,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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