Sulfalene (Sulfametopyrazine, AS-18908) is an orally active antimalarial agent. Sulfalene competes for para-aminobenzoic acid binding in plasmodial folic acid synthesis. Sulfalene, combined with Trimethoprim (HY-B0510), clears parasites, resolves fever, and resists induced resistance against drug-sensitive and drug-resistant Plasmodium falciparum. Sulfalene can be used for the research of acute falciparum malaria and Schistosoma mansoni infection[1][2].
Molekulargewicht:
280.30
Reinheit:
99.73
CAS Nummer:
[152-47-6]
Formel:
C11H12N4O3S
Target-Kategorie:
Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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