Benazepril (CGS14824A) hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril hydrochloride inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. In addition, Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria. Benazepril hydrochloride can be used in the study of hypertension, heart failure and diabetic nephropathy[1][2].
Molekulargewicht:
460.95
Reinheit:
99.96
CAS Nummer:
[86541-74-4]
Formel:
C24H29ClN2O5
Target-Kategorie:
Akt,Angiotensin-converting Enzyme (ACE),Apoptosis,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
Reference compound
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