Risedronic acid (Risedronate) sodium, a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid sodium inhibits blood stages of Plasmodium falciparum (IC50 of 20.3 µM). Risedronic acid sodium inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins[1][2][3].
Molekulargewicht:
305.09
Reinheit:
99.72
CAS Nummer:
[115436-72-1]
Formel:
C7H10NNaO7P2
Target-Kategorie:
Apoptosis,Parasite
Anwendungsbeschreibung:
Reference compound
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