Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate kappa-opioid receptor and octopamine recepto. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full kappa-opioid agonist and dynorphin A-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy[1][2][3][4][5].
Molekulargewicht:
264.36
Reinheit:
99.42
CAS Nummer:
[24219-97-4]
Formel:
C18H20N2
Target-Kategorie:
ERK,Histamine Receptor,Opioid Receptor,p38 MAPK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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