Idoxuridine (5-Iodo-2'-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 µM[1]. Idoxuridine shows anti-orthopoxvirus activity.
Molekulargewicht:
354.10
Reinheit:
99.95
CAS Nummer:
[54-42-2]
Formel:
C9H11IN2O5
Target-Kategorie:
Orthopoxvirus,Phosphatase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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