Almotriptan (hydrochloride)-d6, CAS [[1794782-57-2]]
Artikelnummer:
MCE-HY-B0383AS
Hersteller Artikelnummer:
HY-B0383AS
Alternativnummer:
MCE-HY-B0383AS-5MG,MCE-HY-B0383AS-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
PNU180638 (hydrochloride)-d6
Almotriptan-d6 hydrochloride is the deuterium labeled Almotriptan hydrochloride. Almotriptan (PNU180638 free base) is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan can be used in research related to migraine.
Molekulargewicht:
377.96
Reinheit:
97.30
CAS Nummer:
[1794782-57-2]
Formel:
C17H20D6ClN3O2S
Target-Kategorie:
5-HT Receptor,Isotope-Labeled Compounds
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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