Vardenafil (hydrochloride trihydrate) (Standard), CAS [[330808-88-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-B0442BR
Hersteller Artikelnummer:
HY-B0442BR
Alternativnummer:
MCE-HY-B0442BR-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate). This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4[1]. Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels[2]. Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
