Nitisinone-d3 (NTBC-d3) is deuterium labeled Nitisinone. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism[1][2][3][4].
Molekulargewicht:
332.25
Formel:
C14H7D3F3NO5
Target-Kategorie:
HPPD,Isotope-Labeled Compounds
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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