Metformin (glycinate), CAS [[121369-64-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: Metformin (glycinate), CAS [[121369-64-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-B0627A
• Hersteller Artikelnummer: HY-B0627A
• Alternativnummer: MCE-HY-B0627A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 1,1-Dimethylbiguanide (glycinate)

Produktbeschreibung

Metformin (1,1-Dimethylbiguanide) glycinate inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin glycinate exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin glycinate also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin glycinate regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1][2][3][4][5][6][7][8].

Produkteigenschaften

• Molekulargewicht: 204.23
• CAS Nummer: [121369-64-0]
• Formel: C6H16N6O2
• Target-Kategorie: AMPK,Apoptosis,Autophagy,Mitophagy,mTOR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound