Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-alpha1 (HIF-alpha1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action[1][2][3][4].
Molekulargewicht:
268.27
Reinheit:
99.95
CAS Nummer:
[112901-68-5]
Formel:
C5H21N2O6PS
Target-Kategorie:
HIF/HIF Prolyl-Hydroxylase,MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound
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