Nomifensine (()-Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM and 830 nM, and Ki values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine has antidepressant and analgesic effects. Nomifensine is used in neurodegenerative diseases, compound addiction, and pain research[1][2][3][4][5][6][7].
Molekulargewicht:
238.33
Reinheit:
98.93
CAS Nummer:
[24526-64-5]
Formel:
C16H18N2
Target-Kategorie:
Adrenergic Receptor,Dopamine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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