Dicyclomine hydrochloride is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine hydrochloride shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[1]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[2].
Molekulargewicht:
345.95
Reinheit:
98
CAS Nummer:
[67-92-5]
Formel:
C19H36ClNO2
Target-Kategorie:
mAChR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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