Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 µM[1][2][3].
Molekulargewicht:
356.21
Reinheit:
99.70
CAS Nummer:
[161804-20-2]
Formel:
C13H15Cl2N7O
Target-Kategorie:
Na+/Ca2+ Exchanger,Sodium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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