Carbenoxolone, CAS [[5697-56-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-B1588
Hersteller Artikelnummer:
HY-B1588
Alternativnummer:
MCE-HY-B1588-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Carbenoxolone, a semi-synthetic derivative of glycyrrhetinic acid, has previously been used for the management of dyspepsia and peptic ulcer because of its anti-inflammatory properties[3]. Carbenoxolone, a general hemichannel and gap junction inhibitor, has the therapeutic potential of carbenoxolone in the treatment of chronic liver disease[2]. Carbenoxolone is a suitable candidate for the inhibition of Abeta42 aggregation and the therapeutic potential of Cbx against AD[1]. Carbenoxolone is small molecule Pannexin1 (Panx1,is an ATP release channel) inhibitor, attenuate Panx1 channel activity through modulation of the first extracellular loop[4]. Carbenoxolone is an 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor[5]. Carbenoxolone has antiviral activity against DENV infection targeting the virus itself[6].
Molekulargewicht:
570.76
CAS Nummer:
[5697-56-3]
Formel:
C34H50O7
Target-Kategorie:
Amyloid-beta,HIV
Anwendungsbeschreibung:
MCE Product type: Natural Products
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