Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models[1][2][3].
Molekulargewicht:
433.84
Reinheit:
99.93
CAS Nummer:
[200132-83-8]
Formel:
C14H28ClN3O10
Target-Kategorie:
Antibiotic,Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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