Melperone-d4 (hydrochloride), CAS [[1219798-80-7]]
Artikelnummer:
MCE-HY-B2169S2
Hersteller Artikelnummer:
HY-B2169S2
Alternativnummer:
MCE-HY-B2169S2-500UG,MCE-HY-B2169S2-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Melperone-d4 hydrochloride is the deuterium labeled Melperone hydrochloride (HY-103109)[1]. Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. Melperone hydrochloride is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, alpha1-adrenergic, and alpha2-adrenergic receptors, respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone hydrochloride is also a CYP2D6 inhibitor. Melperone hydrochloride can be used for the study of schizophrenia, and agitation in the elderly[2][3][4][5].
