ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2]. In Vitro: ATP (5 mM, 1 hour) co-treatment with LPS (1 µg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3]. ATP (2 mM, 0.5-24 hours) induces secretion of IL-1beta, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4]. ATP promotes neutrophil chemotaxis in vitro[4]. In Vivo: ATP (50 mg/kg, i.p.) protects mice against bacterial infection in vivo[4]. ATP induces the secretion of IL-1beta, KC and MIP-2 and neutrophils recruitment in vivo[4].
Molekulargewicht:
507.18
Reinheit:
95.70
CAS Nummer:
[56-65-5]
Formel:
C10H16N5O13P3
Target-Kategorie:
Endogenous Metabolite,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
