Propidium monoazide is a photoreactive DNA-binding dye that preferentially binds to dsDNA. Propidium monoazide (PMA) prevents DNA from dead bacteria from being amplified during the PCR. PMA-PCR enhanced both the specificity and the sensitivity of PCR[1]. Propidium monoazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molekulargewicht:
511.49
Reinheit:
99.30
CAS Nummer:
[91416-20-5]
Formel:
C27H32Cl2N6
Target-Kategorie:
Bacterial,Fluorescent Dye
Anwendungsbeschreibung:
MCE Product type: Dye Reagents
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