CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 µM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models[1].
Molekulargewicht:
738.11
CAS Nummer:
[3030055-40-1]
Formel:
C27H23BF2I2N4O2
Target-Kategorie:
Ferroptosis,Photosensitizer,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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