CEMT is a carboxylesterase (CE) substrate and a ratiometric two-photon fluorescent reporter probe. CEMT can be hydrolyzed by CE to generate HMT, which is used for mitochondrial pH sensing. After activation by CE, CEMT exhibits ratiometric fluorescence changes in response to pH variations. CEMT targets and covalently binds to mitochondria, and can avoid leakage during acidification, thus enabling in situ imaging[1].
Molekulargewicht:
482.36
CAS Nummer:
[2413816-64-3]
Formel:
C26H21Cl2NO4
Target-Kategorie:
Fluorescent Dye
Anwendungsbeschreibung:
MCE Product type: Dye Reagents
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