C-HBrO-GGT is a sequence-activated two-photon fluorescent probe. C-HBrO-GGT exhibits sequential fluorescence activation properties: it generates fluorescence in response to hypobromous acid only after being hydrolytically activated by gamma-glutamyl transpeptidase. C-HBrO-GGT enables verification of the voltage-gated chloride channel (CLC-1)-HBrO-catalase (CAT)-GGT signaling pathway at the cellular level. C-HBrO-GGT can serve as a tool to indicate the precise location of mature atherosclerotic plaques and provide early warning of plaque formation. C-HBrO-GGT is applicable to relevant research on atherosclerosis[1].
Molekulargewicht:
480.46
Formel:
C22H19F3N2O5S
Target-Kategorie:
Fluorescent Dye,gamma-Glutamyl Transferase (GGT)
Anwendungsbeschreibung:
MCE Product type: Dye Reagents
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