EGFR T790M/L858R Recombinant Human Active Protein Kinase Preis auf Anfrage

Artikelnummer: MCE-HY-E70711
Artikelname: EGFR T790M/L858R Recombinant Human Active Protein Kinase Preis auf Anfrage
Artikelnummer: MCE-HY-E70711
Hersteller Artikelnummer: HY-E70711
Alternativnummer: MCE-HY-E70711-1UNIT
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR T790M/L858R protein that can be used to study EGFR T790M/L858R-related functions[1].
Target-Kategorie: EGFR
Anwendungsbeschreibung: Enzyme