FGFR1 V561M Recombinant Human Active Protein Kinase Preis auf Anfrage

Produktübersicht

• Artikelname: FGFR1 V561M Recombinant Human Active Protein Kinase Preis auf Anfrage
• Artikelnummer: MCE-HY-E70717
• Hersteller Artikelnummer: HY-E70717
• Alternativnummer: MCE-HY-E70717-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide

Produktbeschreibung

FGFR1 has been implicated in numerous cancer types including non-small cell lung cancer (NSCLC). FGFR1 is activated upon FGF binding to its extracellular domain, resulting in protein dimerization and transautophosphorylation of the intracellular tyrosine kinase domains. FGFR1 V561M gatekeeper mutation drives Fexagratinib (AZD4547) (HY-13330) resistance through STAT3 Activation and EMT. FGFR1 V561M Recombinant Human Active Protein Kinase is a recombinant FGFR1 V561M protein that can be used to study FGFR1 V561M-related functions[1].

Produkteigenschaften

• Target-Kategorie: FGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Enzyme