Indole-2-carboxylic acid, CAS [[1477-50-5]]

Produktübersicht

• Artikelname: Indole-2-carboxylic acid, CAS [[1477-50-5]]
• Artikelnummer: MCE-HY-I0096
• Hersteller Artikelnummer: HY-I0096
• Alternativnummer: MCE-HY-I0096-25G,MCE-HY-I0096-100G,MCE-HY-I0096-10MMX1ML,MCE-HY-I0096-50G,MCE-HY-I0096-10G,MCE-HY-I0096-5G
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (Ki=15 µM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg2+ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection[1][2].

Produkteigenschaften

• Molekulargewicht: 161.16
• Reinheit: 99.97
• CAS Nummer: [1477-50-5]
• Formel: C9H7NO2
• Target-Kategorie: HIV,HIV Integrase,iGluR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products