Beta-Sitosterol (purity>98%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-alpha, IL-1beta, and NF-kappaB p65 and restoring the activity of the HIF-1alpha/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc[1][2][3][4][5][6][7][8][9][10].
Molekulargewicht:
414.71
Reinheit:
99.74
CAS Nummer:
[83-46-5]
Formel:
C29H50O
Target-Kategorie:
Apoptosis,Bacterial,Bcl-2 Family,Caspase,CDK,Glutathione Peroxidase,HIF/HIF Prolyl-Hydroxylase,Interleukin Related,Lactate Dehydrogenase,MDM-2/p53,MMP,mTOR,NF-kappaB,PARP,Reactive Oxygen Species (ROS),SOD,TNF Receptor
Anwendungsbeschreibung:
Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
