(+)-Magnoflorine, CAS [[2141-09-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N0334
Hersteller Artikelnummer:
HY-N0334
Alternativnummer:
MCE-HY-N0334-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Magnoflorine, alpha-Magnoflorine, Thalictrine
(+)-Magnoflorine (alpha-Magnoflorine) is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine inhibits JNK and TLR4/NF-kappaB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-kappaB pathway, and has anti-tumor activity. (+)-Magnoflorine also has significant antifungal activity[1][2][3][4][5][6][7].
Molekulargewicht:
342.41
CAS Nummer:
[2141-09-5]
Formel:
C20H24NO4+
Target-Kategorie:
AMPK,Apoptosis,Autophagy,Caspase,Fungal,JNK,NF-kappaB,NOD-like Receptor (NLR),PINK1/Parkin,Reactive Oxygen Species (ROS),Sirtuin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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