L-Asparagine, CAS [[70-47-3]]

Artikelnummer: MCE-HY-N0667
Artikelname: L-Asparagine, CAS [[70-47-3]]
Artikelnummer: MCE-HY-N0667
Hersteller Artikelnummer: HY-N0667
Alternativnummer: MCE-HY-N0667-25MG,MCE-HY-N0667-50MG,MCE-HY-N0667-100MG,MCE-HY-N0667-1G,MCE-HY-N0667-10MMX1ML,MCE-HY-N0667-500MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: (-)-Asparagine, Asn, Asparamide
L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia[1][2][3][4][5].
Molekulargewicht: 132.12
Reinheit: 98
CAS Nummer: [70-47-3]
Formel: C4H8N2O3
Target-Kategorie: Apoptosis,DNA/RNA Synthesis,Endogenous Metabolite
Anwendungsbeschreibung: MCE Product type: Natural Products