Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities[1]. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE[2]. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters[3].
Molekulargewicht:
355.38
Reinheit:
98.06
CAS Nummer:
[483-43-2]
Formel:
C20H21NO5
Target-Kategorie:
5-HT Receptor,Bacterial,Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Natural Products
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