Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali, possesses the activity of elevating adiponectin production. IC50 value: Target: Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.
Molekulargewicht:
869.04
Reinheit:
99.49
CAS Nummer:
[84676-88-0]
Formel:
C45H72O16
Target-Kategorie:
Others
Anwendungsbeschreibung:
MCE Product type: Natural Products
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