Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 µM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human[1].
Molekulargewicht:
466.57
Reinheit:
99.24
CAS Nummer:
[18385-59-6]
Formel:
C28H34O6
Target-Kategorie:
Parasite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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