Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-beta, and degrades beta-catenin. Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis[1][2].
Molekulargewicht:
638.57
Reinheit:
99.63
CAS Nummer:
[35287-69-5]
Formel:
C32H30O14
Target-Kategorie:
Apoptosis,c-Myc,GSK-3,beta-catenin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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