4'-O-Methylglabridin, CAS [[68978-09-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N11846
Hersteller Artikelnummer:
HY-N11846
Alternativnummer:
MCE-HY-N11846-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
4'-O-Methylglabridin is an apoptosis inducer with antioxidant, cell cycle-disrupting and anticancer cytotoxic activities. 4'-O-Methylglabridin inhibits various cancer cell lines including liver cancer, breast cancer and colorectal cancer cell lines. By reducing the expression levels of phosphorylated Rb (Ser807/811) and p21 proteins, 4'-O-Methylglabridin promotes cell accumulation at the subG1 and G2/M phases, and triggers caspase-dependent apoptosis via cytochrome C release and caspase-9 activation. 4'-O-Methylglabridin also exerts antioxidant effects by inhibiting lipid peroxide levels and reducing beta-carotene consumption, thereby blocking LDL oxidation. 4'-O-Methylglabridin can be used in the research of various cancers and atherosclerotic diseases[1][2].
Molekulargewicht:
338.40
CAS Nummer:
[68978-09-6]
Formel:
C21H22O4
Target-Kategorie:
Apoptosis,Caspase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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