Tubulysin B is a highly cytotoxic peptide and potent microtubule destabilizing agents isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin B has IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties[1].Tubulysin B is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[2].
Molekulargewicht:
830.04
Reinheit:
99.88
CAS Nummer:
[205304-87-6]
Formel:
C42H63N5O10S
Target-Kategorie:
Apoptosis,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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